File:Serpin latent state.png
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Nkomiso
| Description |
English: Some serpins can spontaneously convert to an inactive latent state. The serpin PAI-1 remains in the active conformation when bound to vitronectin (green). However in the absence of vitronectin, PAI-1 can convert to the inactive latent state. The uncleaved RCL (blue, disordered regions as dashed lines) inserts into the A-sheet and the pulls the first β-strand off the C-sheet (yellow). (PDB: 1OC0, 1DVM, 1LJ5) |
| Date | |
| Source | Own work |
| Author | Thomas Shafee |
| Other versions | For unannotated version, see File:Serpin latent state (unannotated).png |
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| Sweswinyana | 23:05, 19 Nyenyankulu 2016 | | 6,454 × 2,922 (7.36 MB) | Evolution and evolvability | Colour tweaks |
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